Scientist-C
M.Sc., Ph.D. (Chemistry) 
Food Chemistry & Nutrient Analysis


Email:   ramesh.gondru@icmr.gov.in
Contact:  +91-40-

Brief Profile

Dr. Gondru Ramesh is currently working in Food Chemistry Division, ICMR−NIN, Hyderabad. He is interested in nutritional and phytochemical analysis of exotic or underutilized fruits and vegetables. He is also interested in evaluating the pharmaceutical importance and isolating bioactive natural products from wild food. Earlier, he worked in Environmental Monitoring & Exposure Assessment Division at ICMR−NIREH, Bhopal, till Jan−2023. He worked on Metal-Organic Frameworks for the adsorptive removal of aromatic volatile organic compounds. He holds a Ph.D. in Chemistry from the National Institute of Technology, Warangal. During his doctoral degree, he worked extensively on synthesizing various new heterocyclic hybrids for medicinal chemistry applications and developed green protocols for synthesizing small bioactive molecules. He also worked as an Assistant Professor (Part-time) in the Department of Chemistry, University Arts & Science College, Kakatiya University, Warangal. He has a guide-ship in Chemistry from VIT−Bhopal and Barkatullah University, Bhopal. He is a regular member of the American Chemical Society (ACS) and a life member of the Indian Council of Chemists (ICC).

Total publications : 27
  1. Palabindela, R.; Guda, R.; Ramesh, G.; Bodapati, R.; Nukala, S. K.; Myadaraveni, P.; Ravi, G.; Kasula, M. Curcumin Based Pyrazole-Thiazole Hybrids as Antiproliferative Agents: Synthesis, Pharmacokinetic, Photophysical Properties, and Docking Studies. J Mol Struct 2023, 1275, 134633. https://doi.org/10.1016/j.molstruc.2022.134633.
  2. K., F.; C. G., A.; Shyam, P.; Gondru, R.; Banothu, J. 1,2,3-Triazole Linked Chalcone-Morpholine Hybrids: Synthesis, In Vitro Antibacterial Evaluation and In Silico ADMET Predictions. Polycycl Aromat Compd 2022, 1–17. https://doi.org/10.1080/10406638.2022.2130369.
  3. Palabindela, R.; Guda, R.; Ramesh, G.; Myadaraveni, P.; Banothu, D.; Ravi, G.; Korra, R.; Mekala, H.; Kasula, M. Novel Tryptanthrin Hybrids Bearing Aminothiazoles as Potential <scp>EGFR</Scp> Inhibitors: Design, Synthesis, Biological Screening, Molecular Docking Studies, and <scp>ADME</Scp> /T Predictions. J Heterocycl Chem 2022, 59 (9), 1533–1550. https://doi.org/10.1002/jhet.4488.
  4. Aher, S. B.; Nandi, S.; Ramesh, G.; Raj, D.; Patel, L.; Tiwari, R. Effects of COVID-19 Lockdown on Ambient Air Pollution in Madhya Pradesh, India. International Journal of Environmental Studies 2022, 79 (3), 401–416. https://doi.org/10.1080/00207233.2021.1929412.
  5. सतीश भागवतराव आहेर, सुब्रोतो नंदी, राजनारायण तिवारी, गोंडरू रमेश. किसान कैसें बचें वायु प्रदुषण से. खेती 2022, 74 (10), 29-30. https://icar.org.in/sites/default/files/Kheti-Feb-2022.pdf.
  6. Mamidala, S.; Aravilli, R. K.; Vaarla, K.; Peddi, S. R.; Gondru, R.; Manga, V.; Vedula, R. R. A Facile One-Pot, Three-Component Synthesis of a New Series of Thiazolyl Pyrazoles: Anticancer Evaluation, ADME and Molecular Docking Studies. Polycycl Aromat Compd 2022, 0 (0), 1–17. https://doi.org/10.1080/10406638.2022.2027788.
  7. G, A. C.; Gondru, R.; Li, Y.; Banothu, J. Coumarin–Benzimidazole Hybrids: A Review of Developments in Medicinal Chemistry. Eur J Med Chem 2022, 227, 113921. https://doi.org/10.1016/j.ejmech.2021.113921.
  8. Arya, C. G.; Chandrakanth, M.; Fabitha, K.; Thomas, N. M.; Pramod, R. N.; Gondru, R.; Banothu, J. Coumarin – Benzimidazole Hybrids: A Review on Diverse Synthetic Strategies. Results Chem 2022, 4, 100631. https://doi.org/10.1016/j.rechem.2022.100631.
  9. Ramya Sucharitha, E.; Krishna, T. M.; Manchal, R.; Ramesh, G.; Narsimha, S. Fused Benzo[1,3]Thiazine-1,2,3-Triazole Hybrids: Microwave-Assisted One-Pot Synthesis, in Vitro Antibacterial, Antibiofilm, and in Silico ADME Studies. Bioorg Med Chem Lett 2021, 47. https://doi.org/10.1016/j.bmcl.2021.128201.
  10. Mamidala, S.; Aravilli, R. K.; Ramesh, G.; Khajavali, S.; Chedupaka, R.; Manga, V.; Vedula, R. R. A Facile One-Pot, Three-Component Synthesis of a New Series of Thiazolyl Pyrazole Carbaldehydes: In Vitro Anticancer Evaluation, in Silico ADME/T, and Molecular Docking Studies. J Mol Struct 2021, 1236, 130356. https://doi.org/10.1016/j.molstruc.2021.130356.
  11. सतीश भागवतराव आहेर, गोंडरू रमेश, सुब्रोतो नंदी, राजनारायण तिवारी. कृषि रसायनों के दुष्प्रभाव से मानव एवं पर्यावरण सुरक्षा. खेती 2021, 74 (1), 49-51. https://icar.org.in/sites/default/files/Kheti-May-2021-min.pdf.
  12. Gondru, R.; Kanugala, S.; Raj, S.; Ganesh Kumar, C.; Pasupuleti, M.; Banothu, J.; Bavantula, R. 1,2,3-Triazole-Thiazole Hybrids: Synthesis, in Vitro Antimicrobial Activity and Antibiofilm Studies. Bioorg Med Chem Lett 2021, 33, 127746. https://doi.org/10.1016/j.bmcl.2020.127746.
  13. Rajitha, G.; Arya, C. G.; Janardhan, B.; Laxmi, S. v.; Ramesh, G.; Kumari, U. S. 3-Aryl/Heteryl-5-Phenylindeno[1,2-d]Thiazolo[3,2-a]Pyrimidin-6(5H)-Ones: Synthesis, Characterization, and Antimicrobial Investigation. Russ J Bioorg Chem 2020, 46 (4), 612–619. https://doi.org/10.1134/S106816202004007X.
  14. Muripiti, V.; Gondru, R.; Patri, S. v. Review of Zinc(II) Scaffolds: Efficient Role in Gene Delivery. ChemistrySelect 2020, 5 (25), 7638–7647. https://doi.org/10.1002/slct.202001557.
  15. Munikumari, G.; Konakanchi, R.; Nishtala, V. B.; Ramesh, G.; Kotha, L. R.; Chandrasekhar, K. B.; Ramachandraiah, C. Palladium(II) Complexes of 5-Substituted Isatin Thiosemicarbazones: Synthesis, Spectroscopic Characterization, Biological Evaluation and in Silico Docking Studies. Synth Commun 2019, 49 (1), 146–158. https://doi.org/10.1080/00397911.2018.1546400.
  16. Gondru, R.; Peddi, S. R.; Manga, V.; Khanapur, M.; Gali, R.; Sirassu, N.; Bavantula, R. One-Pot Synthesis, Biological Evaluation and Molecular Docking Studies of Fused Thiazolo[2,3-b]Pyrimidinone-Pyrazolylcoumarin Hybrids. Mol Divers 2018, 22 (4), 943–956. https://doi.org/10.1007/s11030-018-9845-0.
  17. Konakanchi, R.; Gondru, R.; Nishtala, V. B.; Kotha, L. R. NaF-Catalyzed Efficient One-Pot Synthesis of Dihydropyrano[2,3-c]Pyrazoles under Ultrasonic Irradiation via MCR Approach. Synth Commun 2018, 48 (15), 1994–2001. https://doi.org/10.1080/00397911.2018.1479758.
  18. Gondru, R.; Sirisha, K.; Raj, S.; Gunda, S. K.; Kumar, C. G.; Pasupuleti, M.; Bavantula, R. Design, Synthesis, In Vitro Evaluation and Docking Studies of Pyrazole-Thiazole Hybrids as Antimicrobial and Antibiofilm Agents. ChemistrySelect 2018, 3 (28), 8270–8276. https://doi.org/10.1002/slct.201801391.
  19. Gondru, R.; Saini, R.; Vaarla, K.; Singh, S.; Sirassu, N.; Bavantula, R.; Saxena, A. K. Synthesis and Characterization of Chalcone-Pyridinium Hybrids as Potential Anti-Cancer and Anti-Microbial Agents. ChemistrySelect 2018, 3 (5), 1424–1431. https://doi.org/10.1002/slct.201702971.
  20. Narsimha, S.; Battula, K. S.; Nukala, S. K.; Gondru, R.; Reddy, Y. N.; Nagavelli, V. R. One-Pot Synthesis of Fused Benzoxazino[1,2,3]Triazolyl[4,5-: C] Quinolinone Derivatives and Their Anticancer Activity. RSC Adv 2016, 6 (78), 74332–74339. https://doi.org/10.1039/c6ra12285j.
  21. Ramesh, G.; Gali, R.; Velpula, R.; Rajitha, B. Recyclable Task-Specific Acidic Ionic Liquid [NMP]H2PO4: Microwave-Assisted, Efficient One-Pot, Two-Step Tandem Synthesis of Fused Thiazolo[2,3-b]Quinazolinone and Thiazolo[2,3-b]Quinazoline Derivatives. Research on Chemical Intermediates 2016, 42 (4), 3863–3873. https://doi.org/10.1007/s11164-015-2249-1.
  22. Rajitha, G.; Ravibabu, V.; Ramesh, G.; Rajitha, B. Synthesis and Antimicrobial Activity of Novel Imidazo[1,2-a]Pyridinopyrimidine-2,4,6(1H,3H,5H)-Triones and Thioxopyrimidine-4,6(1H,5H)Diones. Research on Chemical Intermediates 2016, 42 (3), 1989–1998. https://doi.org/10.1007/s11164-015-2130-2.
  23. Rajitha, G.; Ravibabu, V.; Ramesh, G.; Rajitha, B.; Jobina, R.; Siddhardha, B.; Vijaya Laxmi, S. One-Pot Multicomponent Synthesis of Novel Thiazolylhydrazone Derivatives and Their Antimicrobial Activity. Research on Chemical Intermediates 2015, 41 (12), 9703–9713. https://doi.org/10.1007/s11164-015-1959-8.
  24. Ramesh, G.; Janardhan, B.; Rajitha, B. Green Approach: An Efficient Synthesis of 2,4-Disubstituted-1,3-Thiazoles and Selenazoles in Aqueous Medium under Ultrasonic Irradiation. Research on Chemical Intermediates 2015, 41 (11), 8099–8109. https://doi.org/10.1007/s11164-014-1879-z.
  25. Gondru, R.; Banothu, J.; Thatipamula, R. K.; Hussain SK, A.; Bavantula, R. 3-(1-Phenyl-4-((2-(4-Arylthiazol-2-Yl)Hydrazono)Methyl)-1H-Pyrazol-3-Yl)-2H-Chromen-2-Ones: One-Pot Three Component Condensation, in Vitro Antimicrobial, Antioxidant and Molecular Docking Studies. RSC Adv 2015, 5 (42), 33562–33569. https://doi.org/10.1039/C5RA04196A.
  26. Velpula, R.; Gondru, R.; Velivela, Y.; Bavantula, R. Synthesis and Antibacterial Evaluation of Novel 3,6-Disubstituted Coumarin Derivatives. Synth Commun 2015, 45 (5), 578–585. https://doi.org/10.1080/00397911.2014.974612.
  27. Gali, R.; Banothu, J.; Gondru, R.; Bavantula, R.; Velivela, Y.; Crooks, P. A. One-Pot Multicomponent Synthesis of Indole Incorporated Thiazolylcoumarins and Their Antibacterial, Anticancer and DNA Cleavage Studies. Bioorg Med Chem Lett 2015, 25 (1), 106–112. https://doi.org/10.1016/j.bmcl.2014.10.100.
Awards and Honors
  1. Qualified CSIR-UGC-NET-2012 for JRF, Assistant Professor/Lectureship in Chemical Sciences.
  2. Qualified GATE-2012 in Chemistry.
  3. Qualified APSET-2012 in Chemical Sciences.
Current Journal Role (Peer Reviewer)
  1. Journal of Molecular Structures (Elsevier)
  2. Molecular Diversity (Springer)
  3. Research on Chemical Intermediates (Springer)
  4. ChemistrySelect (Wiley-VCH)
  5. Journal of Sulfur Chemistry (Taylor & Francis)